Seminars at the Faculty of Informatics

The Faculty of Informatics is pleased to announce a seminar given by Maria Giuseppina Chiara Nestola

DATE: Thursday, April 2nd, 2015
PLACE: USI Lugano Campus, room SI-013, Informatics building (Via G. Buffi 13)
TIME: 9:30

Patient-specific multiscale fluid-structure interaction (FSI) models are becoming the gold standard approach for validating the performances of biomedical devices and assessing haemodynamic risk in healthy and pathological conditions. The performances of the biological prostheses commonly adopted in the surgical replacement of a diseased aortic valve are compared in terms of mechanical stresses induced by blood within the aortic root wall. To do this aim, a computational study is discussed in terms of FSI simulations in patient-specific geometries. The same methodologies are also adopted to the problem of predictive haemodynamic risk quantification in aneurysms by proposing two new risk indicators based on the recent Three-Band Decomposition analysis applied to the Wall Shear Stress signal. A detailed comparison is conducted with respect to the most common risk indices adopted in the Literature. Finally, the correct definition of the Wall Shear Stress Spatial Gradient is formulated by using the mathematical instruments provided by differential geometry.


  • May 2015 - expected PhD award. Advanced Theoretical Modelling and Fluid-Structure Interaction Analysis of Patient- Specific Cardiovascular Haemodynamics. Advisor Prof. S. Filippi, Co-Advisor Dr. C. Cherubini.
  • 2012 - National Qualification in Professional Engineering in the grade of Industrial Engineering.
  • 2011 - M.S. Biomedical Engineering, UCBM, summa cum laude and merit for the academic career. Prof. Simonetta Filippi, Dr. Christian Cherubini advisors.
    A 3D Fluid-structure interaction model of a viscous Newtonian fluid with ALE formulation. Applications to the haemodynamics of the aorta.
  • 2009 - B.S. Biomedical Engineering, UCBM, summa cum laude and merit for the academic career. Prof. Roberto Setola, Dott.ssa Valentina Russo advisors.
    Tracking motion techniques for deformable organs.

HOST: Prof. Rolf Krause